Naidoo is a CSIR senior researcher in bioengineering and integrative genomics. He obtained a PhD in cell biology from the Institute for Infectious Disease and Molecular Medicine at the University of Cape Town, where his research focused on high content screening and its application to understanding HIV-host interactions. He then undertook a postdoctoral fellowship within the CSIR-UCT Biomedical Translational Research Initiative where he applied HCS and 3D organoid technologies to a functional precision medicine in oncology platform. His current research at the CSIR focuses on precision medicine-based applications, including the development of 3D ‘disease in a dish’ models and the role of the gut microbiome in the context of disease risk and environmental health in South Africa. 

Expertise: Functional precision medicine; Microbiomics and environmental health; Organoid technology and 3D cell culture models; Host pathogen interactions; Phenotypic screening; Functional genomics, micro RNAs and Ex vivo drug screening.  
 

More publications

• Nkera-Gutabara et al., 2022. Microbiomics: The Next Pillar of Precision Medicine and Its Role in African Healthcare. Front. Genet. https://doi.org/10.3389/fgene.2022.869610​
• Hurrell et al., 2022. Hepatic Models in Precision Medicine: An African Perspective on Pharmacovigilance. Front. Genet. https://doi.org/10.3389/fgene.2022.864725​
• Naidoo, J., Hurrell, T., & Scholefield, J. (2022). IPSC-derived models in Africa: An HIV perspective. Biochimie.​
• Naidoo, J., Fok, E., & Scholefield, J. (2019). Therapeutic genome engineering: implications for South Africa. South African Medical Journal, 109(8 Supplement 1), S54-S58.​
• Magagula L, Gagliardi M, Naidoo J, Mhlanga M. (2017) Lnc'g Inflammation to Disease. Under​ review at Biochemical Society Transactions.​
• Scholefield J, Naidoo J, Mhlanga M, Barichievy, S, (2016) PATHOGENIC CONTROL OF APOPTOSIS. International patent filed under Council for Scientific and Industrial Research: WO2016024257 A1​
• Barichievy S, Naidoo J and Mhlanga MM (2015) Non-coding RNAs and HIV: viral manipulation of host dark matter to shape the cellular environment. Front. Genet. 6:108. doi: 10.3389/fgene.2015.00108​
• Naidoo J, Barichievy S, Khutlang R, Mhlanga, M (2015). A METHOD FOR IDENTIFICATION OF ANTI-HIV HUMAN MIRNA MIMICS AND MIRNA INHIBITORS AND ANTI-HIV PHARMACEUTICAL COMPOUNDS. International patent filed under Council for Scientific and Industrial Research. WO/2015/092707​
• Naidoo J, Brackin R, Savulescu A, Khutlang R, and Mhlanga, M (2014) Chapter 5: Systems Biology Tools to Understand the Role of Host MicroRNAs in Infection: a Closer Look at HIV in Applied RNAi: From Fundamental Research to Therapeutic Applications. Caister Academic Press. ed. Patrick Arbuthnot and Marc S. Weinberg​
• Silla, ZTV, Naidoo J, Kidson, SH, Sommer, P. (2014) Signals from the lens and Foxc1 regulate the expression of key genes during the onset of corneal endothelial development. (2014) Experimental Cell Research. 322(2): 381-388.​